abstract：OBJECTIVES:The reliability of two-dimensional echocardiography for determining the proximal coronary artery anatomy in d-loop transposition of the great arteries was investigated in 406 infants who underwent surgical repair at one institution. BACKGROUND:The origin and proximal course of the main coronary arteries can...

journal_title：Journal of the American College of Cardiology

authors： Pasquini L,Sanders SP,Parness IA,Wernovsky G,Mayer JE Jr,Van der Velde ME,Spevak PJ,Colan SD

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:We attempted to determine whether continuous wave Doppler backscatter power could be used to quantify mitral regurgitation. BACKGROUND:The power of a Doppler backscatter signal is proportional to the number of scatterers insonated and, hence, to the moving volume of blood. The relative power of the continuo...

journal_title：Journal of the American College of Cardiology

authors： MacIsaac AI,McDonald IG,Kirsner KL,Graham SA,Gill RW

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:This study was designed to evaluate dobutamine stress echocardiography in identifying reversible dysfunction and assessing the extent of irreversibly damaged myocardium early in acute myocardial infarction. BACKGROUND:Several experimental and clinical studies have suggested that dobutamine enhances contract...

journal_title：Journal of the American College of Cardiology

authors： Watada H,Ito H,Oh H,Masuyama T,Aburaya M,Hori M,Iwakura M,Higashino Y,Fujii K,Minamino T

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVES:This study compared and contrasted the randomized trials of directional atherectomy and coronary angioplasty for de novo native coronary artery lesions. BACKGROUND:The results of two randomized trials, the Coronary Angioplasty Versus Excisional Atherectomy Trial (CAVEAT) and the Canadian Coronary Atherectom...

journal_title：Journal of the American College of Cardiology

authors： Holmes DR Jr,Topol EJ,Adelman AG,Cohen EA,Califf RM

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVES:This study was undertaken to examine the effects of coronary flow dynamics after thrombolysis on infarct size limitation. BACKGROUND:It has been commonly accepted that early thrombolysis does not necessarily salvage infarcted myocardium. Plausible causes for myocardial necrosis include such factors as elaps...

journal_title：Journal of the American College of Cardiology

authors： Komamura K,Kitakaze M,Nishida K,Naka M,Tamai J,Uematsu M,Koretsune Y,Nanto S,Hori M,Inoue M

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVES:This study investigated whether substance P potentiates the muscular and cardiac pain caused by the intraarterial infusion of adenosine, an autocoid known to induce muscular and cardiac ischemic-like pain in humans. BACKGROUND:Substance P is involved in the generation of neurogenic inflammation and causes c...

journal_title：Journal of the American College of Cardiology

authors： Gaspardone A,Crea F,Tomai F,Iamele M,Crossman DC,Pappagallo M,Versaci F,Chiariello L,Gioffrè PA

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:We assessed the production of eicosanoids and the effects of very low dose aspirin in patients with stable angina under basal conditions and during rapid atrial pacing. BACKGROUND:Platelet activation occurs in acute ischemic syndromes but is still controversial in stable angina. Very low dose aspirin is know...

journal_title：Journal of the American College of Cardiology

authors： Montalescot G,Maclouf J,Drobinski G,Salloum J,Grosgogeat Y,Thomas D

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to better understand the effects of long-term right ventricular pacing on left ventricular perfusion, innervation, function and histology. BACKGROUND:Long-term right ventricular apical pacing is associated with increased congestive heart failure and mortality compared with atri...

journal_title：Journal of the American College of Cardiology

authors： Lee MA,Dae MW,Langberg JJ,Griffin JC,Chin MC,Finkbeiner WE,O'Connell JW,Botvinick E,Scheinman MM,Rosenqvist M

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to investigate left atrial appendage size, function and thrombus prevalence in patients with atrial "fibrillation-flutter." BACKGROUND:Thrombus formation and peripheral embolization in atrial fibrillation are related to left atrial appendage dysfunction. Embolization occurs les...

journal_title：Journal of the American College of Cardiology

authors： Santiago D,Warshofsky M,Li Mandri G,Di Tullio M,Coromilas J,Reiffel J,Homma S

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:This study was performed to determine whether cardiac surgery improves functional capacity in patients > 70 years of age and to identify factors associated with good and poor functional results in this age group. BACKGROUND:Cardiac surgery has been used increasingly among older patients, but the effectivene...

journal_title：Journal of the American College of Cardiology

authors： Jaeger AA,Hlatky MA,Paul SM,Gortner SR

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVES:This study evaluated the acute hemodynamic changes with atrial septal defect closure in the postoperative period in patients undergoing the Fontan procedure. BACKGROUND:The adjustable atrial septal defect is a modification of the Fontan procedure designed to improve cardiac output and reduce systemic venous...

journal_title：Journal of the American College of Cardiology

authors： Harake B,Kuhn MA,Jarmakani JM,Laks H,al-Khatib Y,Elami A,Williams RG

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:This study was conducted to determine the yield of transesophageal echocardiographic findings in a consecutive series of patients with stroke and transient ischemic attack, with and without carotid stenosis, and to estimate the recurrent stroke risk associated with specific echocardiographic findings. BACKG...

journal_title：Journal of the American College of Cardiology

authors： Comess KA,DeRook FA,Beach KW,Lytle NJ,Golby AJ,Albers GW

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:We hypothesized that the time course of the recovery of atrial systolic function may be related to the duration of atrial fibrillation before cardioversion and sought to study noninvasively the recovery of left atrial mechanical function utilizing serial transthoracic Doppler studies. BACKGROUND:Recovery of...

journal_title：Journal of the American College of Cardiology

authors： Manning WJ,Silverman DI,Katz SE,Riley MF,Come PC,Doherty RM,Munson JT,Douglas PS

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:This study compared the efficacy and safety of balloon angioplasty with surgical correction of native aortic coarctation in infants < or = 3 months old. BACKGROUND:There is a controversy with regard to the role of balloon angioplasty in the treatment of aortic coarctation, especially in young infants. METH...

journal_title：Journal of the American College of Cardiology

authors： Rao PS,Chopra PS,Koscik R,Smith PA,Wilson AD

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:The present study examined whether sudden death in patients with hypertrophic cardiomyopathy occurred with a particular pattern of frequency throughout the day. BACKGROUND:Previous investigators have shown a circadian distribution in the occurrence of sudden death and other cardiovascular events in patients...

journal_title：Journal of the American College of Cardiology

authors： Maron BJ,Kogan J,Proschan MA,Hecht GM,Roberts WC

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the immediate and follow-up results of percutaneous transatrial mitral commissurotomy in 600 patients with rheumatic mitral stenosis. BACKGROUND:Percutaneous transatrial mitral commissurotomy has emerged as an effective nonsurgical technique for patients with sympto...

journal_title：Journal of the American College of Cardiology

authors： Arora R,Kalra GS,Murty GS,Trehan V,Jolly N,Mohan JC,Sethi KK,Nigam M,Khalilullah M

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:This study evaluated the extent of the collagen network in neonatal heart muscle and whether the type I/type III collagen ratio is the same as in the adult heart. BACKGROUND:The functional integrity and the stress-strain relation of heart muscle depends largely on the extracellular collagen matrix. The ques...

journal_title：Journal of the American College of Cardiology

authors： Marijianowski MM,van der Loos CM,Mohrschladt MF,Becker AE

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVES:A technique for terminating refractory ventricular fibrillation is described. BACKGROUND:Refractory ventricular fibrillation can occur in up to 0.1% of electrophysiologic studies. Animal studies have shown that rapid sequential shocks may reduce ventricular fibrillation threshold. METHODS:Five patients of ...

journal_title：Journal of the American College of Cardiology

authors： Hoch DH,Batsford WP,Greenberg SM,McPherson CM,Rosenfeld LE,Marieb M,Levine JH

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to evaluate the role of percutaneous aortic valvuloplasty in patients with cardiogenic shock due to severe aortic stenosis and associated major comorbid conditions and to establish predictors of survival. BACKGROUND:The prognosis for patients in cardiogenic shock with severe aorti...

journal_title：Journal of the American College of Cardiology

authors： Moreno PR,Jang IK,Newell JB,Block PC,Palacios IF

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVES:This clinical trial was performed to determine the safety and clinical impact of titrated metoprolol therapy in patients with heart failure, documented coronary artery disease and a low ejection fraction. BACKGROUND:Despite known cardiodepressant effects, long-term use of beta-adrenergic antagonists appears...

journal_title：Journal of the American College of Cardiology

authors： Fisher ML,Gottlieb SS,Plotnick GD,Greenberg NL,Patten RD,Bennett SK,Hamilton BP

更新日期：1994-03-15 00:00:00

abstract：OBJECTIVES:This study aimed to determine whether angiographically visualized collateral vessels in patients with chronic coronary artery disease imply the presence of viable myocardium in asynergic regions subtended by completely occluded coronary arteries. BACKGROUND:Patients with chronic coronary artery disease who ...

journal_title：Journal of the American College of Cardiology

authors： Di Carli M,Sherman T,Khanna S,Davidson M,Rokhsar S,Hawkins R,Phelps M,Schelbert H,Maddahi J

更新日期：1994-03-15 00:00:00

abstract：OBJECTIVES:This study was conducted to evaluate the sensitivity and specificity of traditional electrocardiographic (ECG) criteria for right atrial enlargement and identify improve criteria, using quantitative two-dimensional echocardiography. BACKGROUND:Traditional ECG criteria for right atrial enlargement, such as P...

journal_title：Journal of the American College of Cardiology

authors： Kaplan JD,Evans GT Jr,Foster E,Lim D,Schiller NB

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:The effect of dipyridamole on smooth muscle cell proliferation and prevention of intimal thickening after arterial injury was investigated. BACKGROUND:In addition to antiplatelet activity, dipyridamole also inhibits cell proliferation. We examined whether the antiproliferative action of dipyridamole on smoo...

journal_title：Journal of the American College of Cardiology

authors： Singh JP,Rothfuss KJ,Wiernicki TR,Lacefield WB,Kurtz WL,Brown RF,Brune KA,Bailey D,Dubé GP

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:This study was conducted to determine the frequency and significance of Coxsackie B virus-specific immunoglobulin-M (IgM) in patients with idiopathic dilated cardiomyopathy and compare them with the frequency in both unmatched and matched control subjects. BACKGROUND:The principal evidence supporting a path...

journal_title：Journal of the American College of Cardiology

authors： Keeling PJ,Lukaszyk A,Poloniecki J,Caforio AL,Davies MJ,Booth JC,McKenna WJ

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:This study was designed to test the hypothesis that long-term oral supplementation of dietary L-arginine (to provide a sustained elevation of nitric oxide activity) would inhibit atherogenesis in hypercholesterolemic rabbits, as assessed by histomorphometric measurements. BACKGROUND:Endothelium-derived nitr...

journal_title：Journal of the American College of Cardiology

authors： Wang BY,Singer AH,Tsao PS,Drexler H,Kosek J,Cooke JP

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare metabolic risk factors in men with anginal chest pain and a normal or abnormal coronary angiogram with those in healthy men. BACKGROUND:Risk factors for coronary heart disease, including lipoprotein abnormalities, hypertension and adiposity, may be metabolically interlin...

journal_title：Journal of the American College of Cardiology

authors： Ley CJ,Swan J,Godsland IF,Walton C,Crook D,Stevenson JC

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVES:We hypothesized that combining biphasic waveform and sequential pulse defibrillation techniques would lower the defibrillation threshold of a nonthoracotomy lead system in humans below that obtained with biphasic or sequential pulse defibrillation alone. BACKGROUND:Previous studies have shown that sequentia...

journal_title：Journal of the American College of Cardiology

authors： Exner D,Yee R,Jones DL,Klein GJ,Mehra R

更新日期：1994-02-01 00:00:00

abstract：:The management of anticoagulant therapy in patients with atrial fibrillation undergoing electrical cardioversion remains controversial, largely because of inadequate studies demonstrating risk or benefit, a relatively inconvenient anticoagulation management strategy and the increasing use of transesophageal echocardio...

journal_title：Journal of the American College of Cardiology

authors： Grimm RA,Stewart WJ,Black IW,Thomas JD,Klein AL

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to assess the effect of different degrees of ischemia on circulating and cardiac neurohormones and vasotone. BACKGROUND:Neuroendocrine activation and subsequent systemic vasoconstriction may complicate ischemia. Whether this relates to severity of ischemia and subsequent cardia...

journal_title：Journal of the American College of Cardiology

authors： Remme WJ,Kruyssen DA,Look MP,Bootsma M,de Leeuw PW

更新日期：1994-01-01 00:00:00

abstract：:Recent findings point to an important heterogeneity in the electrical behavior of cells spanning the ventricular wall as well as important differences in the response of the various cell types to cardioactive drugs and pathophysiologic states. These observations have permitted a fine tuning and, in some cases, a reeva...

journal_title：Journal of the American College of Cardiology

authors： Antzelevitch C,Sicouri S

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:This report describes the sensing/pacing lead complications that developed during a worldwide clinical trial of a new implantable cardioverter-defibrillator. BACKGROUND:The reliability of the leads used for sensing and pacing with the implantable cardioverter-defibrillator has not been adequately studied. ...

journal_title：Journal of the American College of Cardiology

authors： Stambler BS,Wood MA,Damiano RJ,Greenway PS,Smutka ML,Ellenbogen KA

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the feasibility of re-expansion of balloon expandable intravascular stents and to examine the gross and histologic effects of re-expansion on vascular integrity. BACKGROUND:Intravascular stents have been used successfully as an adjunct to balloon dilation of congeni...

journal_title：Journal of the American College of Cardiology

authors： Morrow WR,Palmaz JC,Tio FO,Ehler WJ,VanDellen AF,Mullins CE

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:The current study was designed to determine the effect of secular trend and referral bias on the natural history of idiopathic dilated cardiomyopathy. BACKGROUND:In a previous study of 104 patients with idiopathic dilated cardiomyopathy conducted in a referral population at the Mayo Clinic between 1960 and ...

journal_title：Journal of the American College of Cardiology

authors： Redfield MM,Gersh BJ,Bailey KR,Ballard DJ,Rodeheffer RJ

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:We hypothesized that intravascular ultrasound may identify significant coronary artery narrowing in the mildly diseased coronary artery of patients with insignificant or one- or two-vessel coronary artery disease. BACKGROUND:Necropsy studies have revealed that coronary angiography may underestimate stenosis...

journal_title：Journal of the American College of Cardiology

authors： Porter TR,Sears T,Xie F,Michels A,Mata J,Welsh D,Shurmur S

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to analyze the feasibility of early discharge (4 days) after acute myocardial infarction in patients not receiving thrombolytic therapy by first identifying predictors of short-term prognosis and then testing the derived risk profile in an independent cohort of patients. BACKGR...

journal_title：Journal of the American College of Cardiology

authors： Sanz G,Betriu A,Oller G,Matas M,Magriñá J,Paré C,Roig E,Heras M,Azqueta M,Bosch X

更新日期：1993-12-01 00:00:00

abstract：:Atrial fibrillation is the most common sustained cardiac arrhythmia encountered in clinical practice. Atrial fibrillation increases with age and is relatively common (> 5%) in patients > 69 years old. Despite this, our understanding of the underlying electrophysiologic mechanisms and the optimal management remains inc...

journal_title：Journal of the American College of Cardiology

authors：

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:To explain the discrepancy between the symptomatic status of patients and the hemodynamically calculated mitral valve area during long-term follow-up after mitral balloon valvulotomy, mitral valve orifice variability after dobutamine infusion was investigated in two groups of patients. BACKGROUND:A signific...

journal_title：Journal of the American College of Cardiology

authors： Okay T,Deligönül U,Sancaktar O,Kozan O

更新日期：1993-11-15 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine whether residual stenoses after excimer laser angioplasty and atherectomy were due to inefficient tissue ablation/removal or to undersized devices. BACKGROUND:Significant residual stenoses are commonly observed after use of laser and atherectomy devices. It is not ...

journal_title：Journal of the American College of Cardiology

authors： Safian RD,Freed M,Lichtenberg A,May MA,Juran N,Grines CL,O'Neill WW

更新日期：1993-11-15 00:00:00

abstract：OBJECTIVES:This study was designed to assess the safety and efficacy of intravenously administered sonicated human serum albumin for enhancing echocardiographic delineation of the left ventricular endocardium and improving assessment of wall motion in patients with incomplete depiction of noncontrast echocardiography. ...

journal_title：Journal of the American College of Cardiology

authors： Crouse LJ,Cheirif J,Hanly DE,Kisslo JA,Labovitz AJ,Raichlen JS,Schutz RW,Shah PM,Smith MD

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine whether pulmonary artery responses to acetylcholine are abnormal in patients with chronic heart failure. BACKGROUND:Defective pulmonary artery endothelium-dependent responses have been observed in chronic heart failure models in animals. However, pulmonary artery e...

journal_title：Journal of the American College of Cardiology

authors： Porter TR,Taylor DO,Cycan A,Fields J,Bagley CW,Pandian NG,Mohanty PK

更新日期：1993-11-01 00:00:00